Patent

U.S. Patent Number	:	5,536,506 USE OF PIPERINE TO INCREASE THE BIOAVAILABILITY OF NUTRITIONAL COMPOUND
Date of Patent	:	July 16, 1996
Inventors	:	Muhammed Majeed, Vladimir Badmaev, R. Rajendran
Assignee	:	Sabinsa Corporation, Piscataway, NJ

ABSTRACT: A new composition and methods for the improvement gastrointestinal absorption and systemic utilization of nutrients and nutritional supplements, wherein the compositions compromises an extract from the fruit of Piper containing a minimum of 98% of pure alkaloid piperine. The method comprises oral, topical, or parenteral administration of the compositions of the invention. A new process for the extraction and purification of piperine is also disclosed.

 

U.S. Patent Number	:	5,744,161 USE OF PIPERINE AS A BIOAVAILABILITY ENHANCER
Date of Patent	:	April 28, 1998
Inventors	:	Muhammed Majeed, Vladimir Badmaev, R. Rajendran
Assignee	:	Sabinsa Corporation, Piscataway, NJ

ABSTRACT: Compositions and methods for the improvement of gastrointestinal absorption and systemic utilization of nutrients and nutritional supplements, wherein the compositions compromise a minimum of 98% of pure alkaloid piperine. The method comprises oral, topical, or parenteral administration of the compositions of the invention. A new process for the extraction and purification of piperine is also disclosed.

 

U.S. Patent Number	:	5,972,382 USE OF PIPERINE AS A BIOAVAILABILITY ENHANCER
Date of Patent	:	October 26, 1999
Inventors	:	Muhammed Majeed, Vladimir Badmaev, R. Rajendran
Assignee	:	Sabinsa Corporation, Piscataway, NJ

ABSTRACT: Compositions and methods for the improvement of gastrointestinal absorption and systemic utilization of nutrients and nutritional supplements, wherein the compositions compromise a minimum of 98% of pure alkaloid piperine. The method comprises oral, topical, or parenteral administration of the compositions of the invention. A new process for the extraction and purification of piperine is also disclosed.

 

U.S. Patent Number	:	6,054,585 PROCESS FOR MAKING HIGH PURITY PIPERINE FOR NUTRITIONAL USE
Date of Patent	:	April 25, 2000
Inventors	:	Muhammed Majeed, Vladimir Badmaev
Assignee	:	Sabinsa Corporation, Piscataway, NJ

ABSTRACT: The present invention relates to a process of making high purity piperine for nutritional and nutraceutical application. This process recovers piperine from piperine-containing oleoresin by using isourea, urea or a urea derivative to remove organic matter other than piperine from the oleoresin. Preferably, the process recovers piperine from oleoresin of fruit of piper nigrum or piper longum. More preferably, the process recovers piperine from oleoresin of fruit of piper nigrum, i.e. black pepper.

 

Europe Patent Number	:	EP0810868 USE OF PIPERINE AS A BIOAVAILABILITY ENHANCER
Date of Patent	:	December 10, 1997
Inventors	:	Muhammed Majeed, Vladimir Badmaev, Rajendran R
Assignee	:	Sabinsa Corporation, Piscataway, NJ

ABSTRACT : Compositions and methods for the improvement of gastrointestinal absorption and systemic utilization of nutrients and nutritional supplements, wherein the compositions comprise a minimum of 98 % of pure alkaloid piperine. The method comprises oral, topical, or parenteral administration of the compositions of the invention. A new process for the extraction and purification of piperine is also disclosed.

 

Japan Patent Number	:	JP3953513 USE OF PIPERINE AS A BIOAVAILABILITY ENHANCER
Date of Patent	:	August 08, 2007
Inventors	:	Muhammed Majeed, Vladimir Badmaev, Rajendran R
Assignee	:	Sabinsa Corporation, Piscataway, NJ

ABSTRACT : Compositions and methods for the improvement of gastrointestinal absorption and systemic utilization of nutrients and nutritional supplements,  wherein the compositions comprise a minimum of 98 % of pure alkaloid piperine. The method comprises oral,  topical,  or parenteral administration of the compositions of the invention. A new process for the extraction and purification of piperine is also disclosed.

 

Canada Patent Number	:	CA2247467 USE OF PIPERINE AS A BIOAVAILABILITY ENHANCER
Date of Patent	:	May 29, 2007
Inventors	:	Muhammed Majeed, Vladimir Badmaev, Rajendran R
Assignee	:	Sabinsa Corporation, Piscataway, NJ

ABSTRACT : Compositions and methods for the improvement of gastrointestinal absorption and systemic utilization of nutrients and nutritional supplements, wherein the compositions comprise a minimum of 98 % of pure alkaloid piperine. The method comprises oral, topical, or parenteral administration of the compositions of the invention. A new process for the extraction and purification of piperine is also disclosed.