β-Carotene
In a double-blind, cross-over study small amount of BioPerine® (5 mg) combined with a formula containing 15 mg of β-carotene, given as a food supplement once a day increased almost 2 - fold the blood levels of β-Carotene in human volunteers.
However, a 60% increase in the area under the curve was observed during the experimental phase (β-carotene + BioPerine®) compared to the control after 14-day supplementation.