Bioavailability of vitamin B6 (100 mg) was evaluated with and without BioPerine®. At 2 h, the maximum serum levels of vitamin B6 was 2.5 times higher in the group receiving BioPerine® as compared to the control group. At 4 h, vitamin B6 levels in the group receiving BioPerine® were 1.4 times higher as compared to the control group.