Bioavailability of coenzyme Q10 (CoQ10) was evaluated with and without BioPerine® supplementation in a double-blind, single dose clinical study. After 21 days of supplementation, co-administration of BioPerine® resulted in an absolute increase in CoQ10 serum levels by 1.12 μg/ml as compared to the absolute increase of 0.85 μg/ml in the control group. A 30% increase was observed in the area under the curve of CoQ10 supplemented with BioPerine® compared to control.
